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H 2 O 2 produced during the oxidative folding of endoplasmic reticulum proteins has been found to regulate the signal transduction process of nuclear factor E2-related factor 2 (Nrf2), which in turn regulates the expression of downstream glutathione peroxidase 8 (GPX8), which in turn can participate in ER calcium regulation through endoplasmic reticulum calcium ATPase (SERCA) (Figure 7)

It has been argued that it is more appropriate to measure "allicin release" using a USP method for assessing drug release from enteric-coated tablets under conditions that mimic those of the stomach and intestine (139)

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